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Culicoides species responsible for the transmission of Epizootic Haemorrhagic Disease virus (EHDV) serotype 8 in Italy
VetIt.3347.22208.1

Keywords

Epizootic hemorrhagic disease virus (EHDV)
Europe
Culicoides
Italy

How to Cite

Quaglia, M., Foxi, C., Satta, G., Puggioni, G. ., Bechere, R. ., De Ascentis, M., d’Alessio, S. G., Spedicato, M. ., Leone, A., Pisciella, M. ., Portanti, O., Teodori, L., Di Gialleonardo, L. ., Cammà, C., Savini, G., & Goffredo, M. (2023). Culicoides species responsible for the transmission of Epizootic Haemorrhagic Disease virus (EHDV) serotype 8 in Italy. Veterinaria Italiana, 59(1). https://doi.org/10.12834/VetIt.3347.22208.1

Funding data

Abstract

Epizootic haemorrhagic disease (EHD) is a viral disease transmitted by Culicoides biting midges that affects wild and domestic ruminants. The causative agent, EHD virus (EHDV), belongs to the family Sedoreoviridae, genus Orbivirus. The virus has never been reported in Europe until October 2022, when the virus was for the first time detected in Sicily and Sardinia. After the first clinical cases, an intensive entomological field activity was carried out in five EHD affected farms located in Sardinia, with the aim of assessing the EHDV vector competence in European species of Culicoides. EHDV‑8 was detected in C. imicola, C. obsoletus/scoticus, C. newsteadi, C. pulicaris ss, and C. bysta. The first 4 species have also been demonstrated to be able to transmit bluetongue virus (BTV). According to these results, it is likely that EHDV‑8, sharing the same transmission patterns of BTV, can also spread to Europe.

https://doi.org/10.12834/VetIt.3347.22208.1
VetIt.3347.22208.1

References

Balenghien T., Pagès N., Goffredo M., Carpenter S., Augot D., Jacquier E., Talavera S., Monaco F., Depaquit J., Grillet C., Pujols J., Satta G., Kasbari M., Setier-Rio M.L., Izzo F., Alkan C., Delécolle J.C., Quaglia M., Charrel R., Polci A., Bréard E., Federici V., Cêtre-Sossah C. & Garros C. 2014. The emergence of Schmallenberg virus across Culicoides communities and ecosystems in Europe. Prev Vet Med. 116(4):360-9. doi: 10.1016/j.prevetmed.2014.03.007. Epub 2014 Mar 18. PMID: 24698329.

Conte A., Goffredo M., Ippoliti C. & Meiswinkel R. 2007. Influence of biotic and abiotic factors on the distribution and abundance of Culicoides imicola and the Obsoletus Complex in Italy. Vet Parasitol, 150, 333-344.

Delécolle J.C. 1985. Nouvelle contribution à l'étude systématique et iconographique des espèces du genre Culicoides (Diptera: Ceratopogonidae) du Nord Est de la France. Thesis, Université Louis Pasteur de Strasbourg, UER Sciences, Vie et Terre, 238 pp.

Dik B., Yavru S., Uslu U., Yapici O. & Esin E. 2012. Determination of Culicoides species (Diptera: Ceratopogonidae) as suspect vectors of epizootic haemorrhagic disease and bluetongue viruses in southern and western Anatolia by RT PCR. Rev Med Vet, 163, 505 510.

Dyce A.L. 1965. The recognition of nulliparous and parous Culicoides (Diptera: Ceratopogonidae) without dissection. J Aust Entomol Soc, 8 (1), 11 15.

European Food Safety Authority (EFSA) & EFSA Panel on Animal Health and Welfare (AHAW). 2009. Scientific Opinion on Epizootic Hemorrhagic Disease. EFSA Journal, 7 (12), 1418.

European Centre for Disease Prevention and Control (ecdc). Biting midge maps (available at https://ecdc.europa.eu/en/disease-vectors/surveillance-and-disease-data/biting-midge-maps. Accessed on 07 July 2023)

Federici V., Ippoliti C., Goffredo M., Catalani M., Di Provvido A., Santilli A., Quaglia M., Mancini G., Di Nicola F., Di Gennaro A., Leone A., Teodori L., Conte A. & Savini G. 2016. Epizootic haemorrhagic disease in Italy: vector competence of indigenous Culicoides species and spatial multicriteria evaluation of vulnerability. Vet Ital. 52(3-4):271-279. doi: 10.12834/VetIt.894.4516.2. PMID: 27723036.

Foxi C., Pinna M., Monteys V. S. I., & Del Rio G. 2011. An updated checklist of the Culicoides Latreille (Diptera: Ceratopogonidae) of Sardinia (Italy), and seasonality in proven and potential vectors for bluetongue virus (BTV). Proc. Entomological Society of Washington, 113(4), 403-416.

Goffredo M. & Meiswinkel R. 2004. Entomological surveillance of bluetongue in Italy: methods of capture, catch analysis and identification of Culicoides biting midges. Vet Ital, 40, 260 265.

Goffredo M., Monaco F., Capelli G., Quaglia M., Federici V., Catalani M., Montarsi F, Polci A., Pinoni C., Calistri P. & Savini G. 2013. Schmallenberg virus in Italy: a retrospective survey in Culicoides stored during the bluetongue Italian surveillance program. Prev Vet Med. 111(3-4):230-6. doi: 10.1016/j.prevetmed.2013.05.014. Epub 2013 Jun 19. PMID: 23791122.

Goffredo M., Catalani M., Federici V., Portanti O., Marini V., Mancini G., Quaglia M., Santilli A., Teodori L. & Savini G. 2015. Vector species of Culicoides midges implicated in the 2012 2014 Bluetongue epidemics in Italy. Vet Ital. 51(2):131-8. doi: 10.12834/VetIt.771.3854.1. PMID: 26129664.

Goffredo M., Meiswinkel R., Federici V., Di Nicola F., Mancini G., Ippoliti C., Di Lorenzo A., Quaglia M., Santilli A., Conte A. & Savini G. 2016. The 'Culicoides obsoletus group' in Italy: relative abundance, geographic range, and role as vector for Bluetongue virus. Vet Ital., 52(3-4):235-241. doi: 10.12834/VetIt.35.100.1. PMID: 27723032.

Hebert P.D., Ratnasingham S. & deWaard J.R. 2003. Barcoding animal life: cytochrome c oxidase subunit 1 divergences among closely related species. Proc Biol Sci., 270 Suppl 1(Suppl 1):S96-9. doi: 10.1098/rsbl.2003.0025.

Hofmann M.A., Renzullo S., Mader M., Chaignat V., Worwa G., & Thuer B. 2008. Genetic characterization of Toggenburg orbivirus, a new bluetongue virus, from goats, Switzerland. Emerg Infect Dis. 14(12), 1855– 1861.

Lorusso A., Sghaier S., Di Domenico M., Barbria M.E., Zaccaria G., Megdich A., Portanti O., Seliman I.B., Spedicato M., Pizzurro F., Carmine I., Teodori L., Mahjoub M., Mangone I., Leone A., Hammami S., Marcacci M. & Savini G. 2018. Analysis of bluetongue serotype 3 spread in Tunisia and discovery of a novel strain related to the bluetongue virus isolated from a commercial sheep pox vaccine. Infect Genet Evol.; 59:63-71. doi: 10.1016/j.meegid.2018.01.025. Epub 2018 Jan 31. PMID: 29386141.

Lorusso A., Cappai S., Loi F., Pinna L., Ruiu A., Puggioni G., Guercio A., Purpari G., Vicari D., Sghaier S., Zientara S., Spedicato M., Hammami S., Ben Hassine T., Portanti O., Breard E., Sailleu C., Ancora M., Di Sabatino D., Morelli D., Calistri P. & Savini G. 2022. Epizootic Hemorrhagic Disease Virus Serotype 8, Italy, Emerg Infect Dis. 2023 May;29(5):1063-1065. doi: 10.3201/eid2905.221773. PMID: 37081599; PMCID: PMC10124640.

Meiswinkel R., Baldet T., De Deken R., Takken W., Delécolle J.C. & Mellor P.S. 2008. The 2006 outbreak of bluetongue in northern Europe the entomological perspective. Prev Vet Med, 87 (1), 55 63.

Mehlhorn H., Walldorf V., Klimpel S., Schaub G., Kiel E., Focke R., Liebisch G., Liebisch A., Werner D., Bauer C., Clausen H., Bauer B., Geier M., Hörbrand T., Bätza H.J., Conraths F.J., Hoffmann B. & Beer M. 2009. Bluetongue disease in Germany (2007-2008): monitoring of entomological aspects. Parasitol Res., 105(2):313-9. doi: 10.1007/s00436-009-1416-y. Epub 2009 Mar 26. PMID: 19322587.

Mullen G.R., Hayes M.E. & Nusbaum K.E. 1985. Potential vectors of bluetongue and epizootic hemorrhagic disease viruses of cattle and white tailed deer in Alabama. Progr Clin Biol Res, 178, 201 206

Paweska J.T., Venter G.J. & Hamblin C. 2005. A comparison of the susceptibility of Culicoides imicola and C. bolitinos to oral infection with eight serotypes of epizootic haemorrhagic disease virus. Med Vet Entomol, 19 (2), 200 207.

Sarvašová A., Kočišová A., Candolfi E. & Mathieu B. 2017. Description of Culicoides (Culicoides) bysta n. sp., a new member of the Pulicaris group (Diptera: Ceratopogonidae) from Slovakia. Parasit Vectors. 10(1):279. doi: 10.1186/s13071-017-2195-4. PMID: 28578677; PMCID: PMC5457568.

Savini G., Afonso A., Mellor P., Aradaib I., Yadin H., Sanaa M., Wilson W., Monaco F. & Domingo M. 2011. Epizootic haemorrhagic disease. Res Vet Sci, 91, 1 17.

Sghaier S., Sailleau C., Marcacci M., Thabet S., Curini V., Ben Hassine T., Teodori L., Portanti O., Hammami S., Jurisic L., Spedicato M., Postic L., Gazani I., Ben Osman R., Zientara S., Bréard E., Calistri P., Richt J.A., Holmes E.C., Savini G., Di Giallonardo F. & Lorusso A. 2022. Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021. Viruses. 15(1):16. doi: 10.3390/v15010016. PMID: 36680057; PMCID: PMC9866946.

Shope R.E., MacNamara L.G. & Mangold R., 1955. Epizootic Haemorragic Disease of deer. New Jersey Outdoors (November) 16, 21.

Copyright (c) 2023 Michela Quaglia, Cipriano Foxi, Giuseppe Satta, Giantonella Puggioni, Robero Bechere, Matteo De Ascentis, Silvio Gerardo d'Alessio, Massimo Spedicato, Alessandra Leone, Maura Pisciella, Ottavio Portanti, Liana Teodori, Luigina Di Gialleonardo, Cesare Cammà, Giovanni Savini, Maria Goffredo