Odontoameloblastoma in the posterior maxilla of a -6-years-old Ardi goat (Capra aegagrus hircus)


Odontogenic tumors

How to Cite

El-Shafaey, E.-S. A., Hamed, M., & Dewidar, Z. (2021). Odontoameloblastoma in the posterior maxilla of a -6-years-old Ardi goat (Capra aegagrus hircus). Veterinaria Italiana, 57(3). https://doi.org/10.12834/VetIt.1824.9678.2


A 6‑year‑old female Ardi goat was presented for evaluation of an expansile firm painless maxillary ovoid mass. Clinical and diagnostic imaging
examination revealed a well‑ demarcated extensive mass occupying the left posterior maxilla and altering its anatomical features. Surgical excision was not deemed feasible with this apparently extensive infiltrative features of the tumor and the owner elected to euthanize the goat. Gross examination of the mass showed a grayish‑brown, multiloculated firm and gritty mass measuring 21 x 11 x 19 cm located on the left posterior maxilla. Histopathological examination revealed plexiform and follicular arranged, ameloblast ‑like odontogenic epithelium. Follicular epithelium was disintegrated leaving spaces, identical to solid multicystic ameloblastoma, intermingled with primitive myxoid stroma resembling dental papilla, teeth like hard structure as enamel and dentine, and osteodentine matrix. Based on these findings, the tumor was diagnosed as odontoameloblastoma (OA) and to our knowledge this is the first report of OA in goats.



Barnes L., Eveson J., Reichart P. & Sidransky D. 2005. Odontoameloblastoma. In Pathology and Genetics of Head and Neck Tumors (WHO Classification of Tumors series). Lyon, France, IARC Press, 312.

Burrough E.R., Myers R.K. & Whitley E.M. 2010. Spontaneous odontoameloblastoma in a female Sprague Dawley rat. J Vet Diagn Invest, 22, 998-1001.

Dive A., Khandekar S., Bodhade A. & Dhobley A. 2011. Odontoameloblastoma. J Oral Maxillofac Pathol, 15, 60 -64.

Dubielzig R.R. 2003. Histologic classification of tumors of odontogenic origin of domestic animals. In Histological Classification of Tumors of the Alimentary System of Domestic Animals, vol. 10, 46–57. Washington, DC, Armed Forces Institute of Pathology.

Dubielzig R.R. & Griffith J.W. 1982. An odontoameloblastoma in an adult sheep. Vet Pathol, 19, 318-320.

Lepri E., Avallone G., Mandara M.T. & Vitellozzi G. 2013. Odontoameloblastoma in a calf. J Vet Dent, 30, 248–250.

Gardner D.G. 1996. Ameloblastic fibromas and related tumors in cattle. J Oral Pathol Med, 25, 119–124.

Head K.W., Else R.W. & Dubielzig R.R. 2002. Tumors of the Alimentary Tract. In Tumors in Domestic Animals (Meuten D.J., ed.). 4th ed. Iowa State Press, Avenue, Ames, Iowa, 401–481.

Kok M., Chambers J., Ushio N., Miwa Y., Nakayama H. & Uchida K. 2018. Amyloid-producing Odontoameloblastoma in a Black-tailed Prairie Dog (Cynomys ludovicianus). J Comp Path, 159, 26-30.

Mendez-Angulo J.L., Tatarniuk D.M., Ruiz I. & Ernst N. 2014. Extensive rostral mandibulectomy for treatment of ameloblastoma in a horse. Vet Surg, 43, 222–226.

Mosqueda-Taylor A., Carlos-Bregni R., Ramirez-Amador V., Palma-Guzman J.M., Esquivel-Bonilla D. & Hernandez-Rojase L.A. 2002. Odontoameloblastoma. Clinic-pathologic study of three cases and critical review of the literature. Oral Oncol, 38, 800-805.

Murphy B., Bell C., Koehne A., Richard R. & Dubielzig R. 2017. Mandibular odontoameloblastoma in a rat and a horse. J Vet Diagn Invest, 29, 536–540.

Thompson I.O., Phillips V.M., Ferreira R. & Housego T.G. 1990. Odontoameloblastoma: A case report. Br J Oral Maxillofac Surg, 28, 347‑349.

Wong H., Hedley J., Stapleton N., Murphy B. & Priestnall S. 2018. Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig. J Vet Diagn Invest, 30, 793–797.

Yanai T., Masegi T., Tomita A., Kudo T., Yamazoe K., Iwasaki T., Kimura N., Katou A., Kotera S. & Ueda K. 1995. Odontoameloblastoma in a Japanese Monkey (Macaca fuscata). Vet Pathol, 32, 57-59.