Abstract
Emerging and re-emerging viral diseases shared between wildlife and domestic animals are continually spreading to new geographic locations, influenced by human activities and environmental change. Canine distemper (CD) is probably one of the best examples of a disease that has been proved to be capable of compromising the conservation of several wild carnivore species. In this article, we describe a case report of CD in a grey wolf (Canis lupus) in Iran. A grey wolf was found in Fars Province close to Bamou national park. Clinical signs were characterized by neurologic signs, muscle twitching, hyperkeratosis of the footpads and nose and keratoconjunctivitis sicca. After the death of the animal, samples were taken from different organs and sent to collaborator laboratory of Fars Provincial Office of Veterinary Organization. RT-PCR assays confirmed canine distemper virus in the grey wolf. This is the first documented report of canine distemper virus in wild species from Fars Province of Iran.
References
Oleaga A., Vázquez C.D., Royo L.J., Barral T.D., Bonnaire D., Armenteros J.Á., Rabanal B., Gortázar C. & Balseiro A. 2021. Canine distemper virus in wildlife in south-western Europe. Transbound Emerg Dis. 69, 473-785.
Alfano F., Lanave G., Lucibelli M.G., Miletti G., D’Alessio N., Gallo A., Auriemma C., Amoroso M.G., Lucente M.S., De carlo E., Martella V., Decaro N. & Fusco G. 2022. Canine Distemper Virus in Autochtonous and Imported Dogs, Southern Italy (2014–2021). Animals. 12, 2852.
Tariq A., Shahzad A., Tahira S. 2013. Clinical Aspects of Canine Distemper in 1.5 Year Old Labrador Retriever Bitch. j. vet. pract. 1 (2): 20 – 22.
Namroodi S., Rostami A., Majidzadeh-Ardebili K., Ghalyanchi langroudi A. & Morovvati A. 2015. Detection of Arctic and European cluster of canine distemper virus in north and center of Iran. Veterinary Research Forum. 6 (3), 199-204.
Zarei F., Kafaei S. & Esmaeili H.R. 2019. Annotated checklist and conservation status of mammals of Fars Province, southern Iran. Journal of Threatened Taxa. 11, 13087-13113.
Megid J., De souza V.A.F., Teixeira C.R., Cortez A., Amorin R.L., Heinemman M.B., Cagnini D.Q. & Richtzenhain l.J. 2009. Canine Distemper Virus in a Crab-eating Fox (Cerdocyon thous) in Brazil: Case Report and Phylogenetic Analyses. Journal of Wildlife Diseases. 45. 527-530.
Sarchahi, A.A., Arbabi M. & Mohebalian H. 2022. Detection of canine distemper virus in cerebrospinal fluid, whole blood and mucosal specimens of dogs with distemper using RT-PCR and immunochromatographic assays. Vet Med Sci. 8, 1390-1399.
Memarian I., Zahedian B., Kwaak T., Lippert M., Jazayeri G., Kordestani H., Amirahmadi M. & Nabiyan javardi S.M. 2022. Free Ranging Dogs Impact on Wildlife in North and East of Tehran, Iran. Proceedings Of the Zoo and Wildlife Health Conference, 25-28 May, Emmen, The Netherlands, pp. 15-24.
Di Francesco C., Smoglica C., Paoletti B., Angelucci S., Innocenti M., Antonucci A., Di Domenico G. & Marsilio f. 2019. Detection of selected pathogens in Apennine wolf (Canis lupus italicus) by a non-invasive GPS-based telemetry sampling of two packs from Majella National Park, Italy. European Journal of Wildlife Research. 65.
Allen D.G., Constable P.D., Dart A., Davies P.R., Quesenberry K.E., Reeves P.T. & Sharma J.M. 2016. The Merck Veterinary Manual, 11th ed. Merck & Co., Inc, USA, pp. 777-779.
Greene C.E. & Vandevelde M. 2012. Canine Distemper. In Infectious Dieseases of The Dog and Cat, 4h Edition. (C.E. Greene). Saunders Elsevier, St. Louis, pp. 25-42.
Williams E.S. 2001. Canine Distemper. In Infectious Diseases of Wild Mammals, 3rd Ed (E.S. Williams & I. K. Barker). Iowa State University Press, pp. 50_59.
Sykes J.E. 2014. Canine Distemper Virus Infection. In Canine and Feline Infectious Diseases. (J.E. Sykes). Elsevier, St. Louis, pp.158-165.
Roelke-Parker M.E., Munson L., Packer C., Kock R., Cleaveland S., Carpenter M., O'Brien S.J., Pospischil A., Hofmann-Lehmann R., Lutz H., Mwamengele G.L.M., Mgasa M.N., Machange G.A., Summers B.A. & Appel M.J.G. 1996. A canine distemper virus epidemic in Serengeti lions (Panthera leo). Nature. 379, 441-445.
Mamaev L.V., Denikina N.N., Belikov SI., Volchkov V.E., Visser I.K., Fleming M., Kai C., Harder T.C., Liess B., Osterhaus A.D.M.E. & Barrett T. 1995. Characterisation of morbilliviruses isolated from Lake Baikal seals (Phoca sibirica). Veterinary microbiology. 44, 251-259.
Van de Bildt M.W., Kuiken T., Visee A.M., Lema S., Fitzjohn T.R. & Osterhaus A.D. 2002. Distemper outbreak and its effect on African wild dog conservation. Emerg Infect Dis. 8, 211-213.
Kuiken T., Kennedy S., Barrett T., Van de Bildt M.W., Borgsteede F.H., Brew S.D., Codd G.A., Duck C., Deaville R., Eybatov T., Forsyth M.A., Foster G., Jepson P.D., Kydyrmanov A., Mitrofanov I., Ward C.J., Wilson S. & Osterhaus A.D. 2006. The 2000 canine distemper epidemic in Caspian seals (Phoca caspica): pathology and analysis of contributory factors. Vet Pathol. 43, 321–338.